2QDS

Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril

Summary for 2QDS

• Entry DOI: 10.2210/pdb2qds/pdb
• Related: 1X8G 1X8I 2GKL
• Descriptor: Beta-lactamase, ZINC ION, SULFATE ION, ... (6 entities in total)
• Functional Keywords: hydrolase, lactamase, inhibitor, zn
• Biological source: Aeromonas hydrophila
• Cellular location: Periplasm (Probable): P26918
• Total number of polymer chains: 1
• Total formula weight: 26071.95

Authors

Garau, G.,Dideberg, O. (deposition date: 2007-06-21, release date: 2007-07-17, Last modification date: 2023-08-30)

• Primary citation: Lienard, B.M.,Garau, G.,Horsfall, L.,Karsisiotis, A.I.,Damblon, C.,Lassaux, P.,Papamicael, C.,Roberts, G.C.,Galleni, M.,Dideberg, O.,Frere, J.M.,Schofield, C.J.; Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.; Org.Biomol.Chem., 6:2282-2294, 2008; PubMed: 18563261; DOI: 10.1039/b802311e

Experimental method

X-RAY DIFFRACTION (1.66 Å)