2PWV

tRNA guanine transglycosylase E235Q mutant in complex with preQ0

Summary for 2PWV

Entry DOI	10.2210/pdb2pwv/pdb
Related	1P0B 2PWU
Descriptor	Queuine tRNA-ribosyltransferase, ZINC ION, 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, ... (5 entities in total)
Functional Keywords	tgt, e235q mutant, preq0, transferase
Biological source	Zymomonas mobilis
Total number of polymer chains	1
Total formula weight	43717.84
Authors	Tidten, N.,Stengl, B.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2007-05-13, release date: 2007-10-30, Last modification date: 2023-08-30)
Primary citation	Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K. Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies. J.Mol.Biol., 374:764-776, 2007 Cited by PubMed: 17949745 DOI: 10.1016/j.jmb.2007.09.062 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation