2PQW

Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), trigonal form

Summary for 2PQW

• Entry DOI: 10.2210/pdb2pqw/pdb
• Related: 2RJC 2RJD 2RJE 2RJF
• Descriptor: Lethal(3)malignant brain tumor-like protein, Histone H4, ACETATE ION, ... (4 entities in total)
• Functional Keywords: l(3)mbt-like protein, structural genomics, structural genomics consortium, sgc, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9Y468
• Total number of polymer chains: 2
• Total formula weight: 38513.15

Authors

Allali-Hassani, A.,Liu, Y.,Herzanych, N.,Ouyang, H.,Mackenzie, F.,Crombet, L.,Loppnau, P.,Kozieradzki, I.,Vedadi, M.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.R.,Structural Genomics Consortium (SGC) (deposition date: 2007-05-02, release date: 2007-07-31, Last modification date: 2023-08-30)

• Primary citation: Min, J.,Allali-Hassani, A.,Nady, N.,Qi, C.,Ouyang, H.,Liu, Y.,MacKenzie, F.,Vedadi, M.,Arrowsmith, C.H.; L3MBTL1 recognition of mono- and dimethylated histones.; Nat.Struct.Mol.Biol., 14:1229-1230, 2007; PubMed: 18026117; DOI: 10.1038/nsmb1340

Experimental method

X-RAY DIFFRACTION (2 Å)