2POU
The crystal structure of the human carbonic anhydrase II in complex with 4,5-dichloro-benzene-1,3-disulfonamide
Summary for 2POU
| Entry DOI | 10.2210/pdb2pou/pdb |
| Related | 2POV 2POW |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE, ... (4 entities in total) |
| Functional Keywords | carbonic anhydrase ii, protein-inhibitor complexes, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29659.63 |
| Authors | Alterio, V.,De Simone, G. (deposition date: 2007-04-27, release date: 2007-07-24, Last modification date: 2023-08-30) |
| Primary citation | Alterio, V.,De Simone, G.,Monti, S.M.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides-Solution and crystallographic studies. Bioorg.Med.Chem.Lett., 17:4201-4207, 2007 Cited by PubMed: 17540563DOI: 10.1016/j.bmcl.2007.05.045 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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