2PNR

Crystal Structure of the asymmetric Pdk3-l2 Complex

Summary for 2PNR

• Entry DOI: 10.2210/pdb2pnr/pdb
• Related: 1Y8N
• Descriptor: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, DIHYDROLIPOIC ACID, ... (4 entities in total)
• Functional Keywords: pyruvate dehydrogenase kinase 3, lipoyl-bearing domain, asymmetric protein-protein complex, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion matrix: Q15120 P10515
• Total number of polymer chains: 6
• Total formula weight: 221964.80

Authors

Vassylyev, D.G.,Steussy, C.N.,Devedjiev, Y. (deposition date: 2007-04-25, release date: 2007-08-21, Last modification date: 2023-08-30)

• Primary citation: Devedjiev, Y.,Steussy, C.N.,Vassylyev, D.G.; Crystal Structure of an Asymmetric complex of Pyruvate Dehydrogenase Kinase 3 with Lipoyl domain 2 and its Biological Implications; J.Mol.Biol., 370:407-416, 2007; PubMed: 17532006; DOI: 10.1016/j.jmb.2007.04.083

Experimental method

X-RAY DIFFRACTION (2.5 Å)