2P1D

Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine

2P1D の概要

• エントリーDOI: 10.2210/pdb2p1d/pdb
• 関連するPDBエントリー: 1L9K
• 分子名称: type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• 機能のキーワード: vizier; viral enzymes involved in replication; dengue virus methyltransferase; structural genomics; marseilles structural genomics program @ afmb; msgp, vizier. viral enzymes involved in replication, viral protein, transferase
• 由来する生物種: Dengue virus 2
• 細胞内の位置: Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9WLZ8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36105.29

構造登録者

Egloff, M.P.,Benarooch, D.,Marseilles Structural Genomics Program @ AFMB (MSGP) (登録日: 2007-03-05, 公開日: 2007-03-20, 最終更新日: 2023-08-30)

• 主引用文献: Egloff, M.P.,Benarroch, D.,Selisko, B.,Romette, J.L.,Canard, B.; An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization; EMBO J., 21:2757-2768, 2002; PubMed: 12032088; DOI: 10.1093/emboj/21.11.2757

実験手法

X-RAY DIFFRACTION (2.9 Å)