2OVP

Structure of the Skp1-Fbw7 complex

Summary for 2OVP

• Entry DOI: 10.2210/pdb2ovp/pdb
• Related: 2OVQ 2OVR
• Descriptor: S-phase kinase-associated protein 1A, F-box/WD repeat protein 7 (3 entities in total)
• Functional Keywords: f-box; wd40 domains, transcription-cell cycle complex, transcription/cell cycle
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Nucleus, nucleoplasm. Isoform 2: Cytoplasm. Isoform 4: Nucleus, nucleolus. Nucleus (By similarity): Q969H0
• Total number of polymer chains: 2
• Total formula weight: 67132.57

Authors

Hao, B.,Oehlmann, S.,Sowa, M.E.,Harper, J.W.,Pavletich, N.P. (deposition date: 2007-02-14, release date: 2007-04-24, Last modification date: 2024-04-03)

• Primary citation: Hao, B.,Oehlmann, S.,Sowa, M.E.,Harper, J.W.,Pavletich, N.P.; Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases; Mol.Cell, 26:131-143, 2007; PubMed: 17434132; DOI: 10.1016/j.molcel.2007.02.022

Experimental method

X-RAY DIFFRACTION (2.9 Å)