2OUH

Crystal structure of the Thrombospondin-1 N-terminal domain in complex with fractionated Heparin DP10

Summary for 2OUH

Entry DOI	10.2210/pdb2ouh/pdb
Related	1Z78 1ZA4 2OUJ
Descriptor	Thrombospondin-1, SULFATE ION (3 entities in total)
Functional Keywords	tsp-1, tspn-1, hbd, fractionated heparin, dp10, cell adhesion
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	55688.58
Authors	Tan, K.,Joachimiak, A.,Wang, J.,Lawler, J. (deposition date: 2007-02-11, release date: 2008-01-08, Last modification date: 2023-08-30)
Primary citation	Tan, K.,Duquette, M.,Liu, J.H.,Shanmugasundaram, K.,Joachimiak, A.,Gallagher, J.T.,Rigby, A.C.,Wang, J.H.,Lawler, J. Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain. J.Biol.Chem., 283:3932-3941, 2008 Cited by PubMed: 18065761 DOI: 10.1074/jbc.M705203200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation