2OT1
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with naphthol AS-E phosphate, a competitive inhibitor
Summary for 2OT1
| Entry DOI | 10.2210/pdb2ot1/pdb |
| Descriptor | Fructose-bisphosphate aldolase A, N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE (3 entities in total) |
| Functional Keywords | glycolysis, competitive inhibition, hydrophobic pocket, lyase |
| Biological source | Oryctolagus cuniculus (rabbit) |
| Total number of polymer chains | 4 |
| Total formula weight | 158565.55 |
| Authors | St-Jean, M.,Izard, T.,Sygusch, J. (deposition date: 2007-02-07, release date: 2007-02-27, Last modification date: 2023-08-30) |
| Primary citation | St-Jean, M.,Izard, T.,Sygusch, J. A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with wiskott-Aldrich syndrome protein. J.Biol.Chem., 282:14309-14315, 2007 Cited by PubMed: 17329259DOI: 10.1074/jbc.M611505200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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