2OGV

Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain

Summary for 2OGV

Entry DOI	10.2210/pdb2ogv/pdb
Descriptor	Macrophage colony-stimulating factor 1 receptor precursor (2 entities in total)
Functional Keywords	receptor tyrosine kinase, macrophage colony stimulating factor receptor, transferase
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Single-pass type I membrane protein: P07333
Total number of polymer chains	1
Total formula weight	35791.06
Authors	Walter, M.,Lucet, I.S.,Patel, O.,Broughton, S.E.,Bamert, R.,Williams, N.K.,Fantino, E.,Wilks, A.F.,Rossjohn, J. (deposition date: 2007-01-09, release date: 2007-02-06, Last modification date: 2023-08-30)
Primary citation	Walter, M.,Lucet, I.S.,Patel, O.,Broughton, S.E.,Bamert, R.,Williams, N.K.,Fantino, E.,Wilks, A.F.,Rossjohn, J. The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain. J.Mol.Biol., 367:839-847, 2007 Cited by PubMed: 17292918 DOI: 10.1016/j.jmb.2007.01.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation