2OFP

Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate

Summary for 2OFP

Entry DOI	10.2210/pdb2ofp/pdb
Related	1KS9 1YJQ 1YON
Descriptor	Ketopantoate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PANTOATE, ... (6 entities in total)
Functional Keywords	pane, apba, ketopantoate reductase, ternary complex, oxidoreductase
Biological source	Escherichia coli K12
Cellular location	Cytoplasm (Potential): P0A9J4
Total number of polymer chains	2
Total formula weight	73866.31
Authors	Ciulli, A.,Chirgadze, D.Y.,Smith, A.G.,Blundell, T.L.,Abell, C. (deposition date: 2007-01-04, release date: 2007-01-16, Last modification date: 2023-08-30)
Primary citation	Ciulli, A.,Chirgadze, D.Y.,Smith, A.G.,Blundell, T.L.,Abell, C. Crystal Structure of Escherichia coli Ketopantoate Reductase in a Ternary Complex with NADP+ and Pantoate Bound: SUBSTRATE RECOGNITION, CONFORMATIONAL CHANGE, AND COOPERATIVITY. J.Biol.Chem., 282:8487-8497, 2007 Cited by PubMed: 17229734 DOI: 10.1074/jbc.M611171200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation