2OD2

Crystal Structure of yHst2 I117F mutant bound to carba-NAD+ and an acetylated H4 peptide

Summary for 2OD2

• Entry DOI: 10.2210/pdb2od2/pdb
• Related: 1SZC 1SZD 2OD7 2OD9
• Descriptor: NAD-dependent deacetylase HST2, Acetylated H4 peptide, ZINC ION, ... (6 entities in total)
• Functional Keywords: zn binding protein, rossmann fold, hydrolase
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Cytoplasm: P53686
• Total number of polymer chains: 2
• Total formula weight: 37536.01

Authors

Sanders, B.D. (deposition date: 2006-12-21, release date: 2007-02-20, Last modification date: 2024-04-03)

• Primary citation: Sanders, B.D.,Zhao, K.,Slama, J.T.,Marmorstein, R.; Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.; Mol.Cell, 25:463-472, 2007; PubMed: 17289592; DOI: 10.1016/j.molcel.2006.12.022

Experimental method

X-RAY DIFFRACTION (2 Å)