2OC3

Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 18

Summary for 2OC3

Entry DOI	10.2210/pdb2oc3/pdb
Related	1GWZ 2B49
Descriptor	Tyrosine-protein phosphatase non-receptor type 18 (2 entities in total)
Functional Keywords	protein tyrosine phosphatase, receptor, human, structural genomics, structural genomics consortium, sgc, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q99952
Total number of polymer chains	1
Total formula weight	34296.28
Authors	Ugochukwu, E.,Barr, A.,Alfano, I.,Gorrec, F.,Umeano, C.,Savitsky, P.,Sobott, F.,Eswaran, J.,Papagrigoriou, E.,Debreczeni, J.E.,Turnbull, A.,Bunkoczi, G.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-12-20, release date: 2007-01-30, Last modification date: 2023-08-30)
Primary citation	Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136:352-363, 2009 Cited by PubMed: 19167335 DOI: 10.1016/j.cell.2008.11.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation