2OA6

Aristolochene synthase from Aspergillus terreus complexed with pyrophosphate

Summary for 2OA6

• Entry DOI: 10.2210/pdb2oa6/pdb
• Related: 2E4O
• Descriptor: Aristolochene synthase, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: sesquiterpene cyclase, magnesium, pyrophosphate, farnesyl diphosphate, cyclization, lyase
• Biological source: Aspergillus terreus
• Total number of polymer chains: 4
• Total formula weight: 146748.36

Authors

Shishova, E.Y.,Di Costanzo, L.,Cane, D.E.,Christianson, D.W. (deposition date: 2006-12-15, release date: 2007-01-30, Last modification date: 2023-11-15)

• Primary citation: Shishova, E.Y.,Di Costanzo, L.,Cane, D.E.,Christianson, D.W.; X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate; Biochemistry, 46:1941-1951, 2007; PubMed: 17261032; DOI: 10.1021/bi0622524

Experimental method

X-RAY DIFFRACTION (2.15 Å)