2O6L

Crystal Structure of the UDP-Glucuronic Acid Binding Domain of the Human Drug Metabolizing UDP-Glucuronosyltransferase 2B7

Summary for 2O6L

Entry DOI	10.2210/pdb2o6l/pdb
Descriptor	UDP-glucuronosyltransferase 2B7 (2 entities in total)
Functional Keywords	drug metabolism, rossman, mad, enzyme, nucleotide binding, sugar, udp-glucuronosyltransferase, ugt, transferase
Biological source	Homo sapiens (human)
Cellular location	Microsome membrane; Single-pass membrane protein (Potential): P16662
Total number of polymer chains	2
Total formula weight	38251.44
Authors	Miley, M.J.,Redinbo, M.R. (deposition date: 2006-12-07, release date: 2007-05-01, Last modification date: 2023-12-27)
Primary citation	Miley, M.J.,Zielinska, A.K.,Keenan, J.E.,Bratton, S.M.,Radominska-Pandya, A.,Redinbo, M.R. Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7. J.Mol.Biol., 369:498-511, 2007 Cited by PubMed: 17442341 DOI: 10.1016/j.jmb.2007.03.066 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation