2O26

Structure of a class III RTK signaling assembly

Summary for 2O26

• Entry DOI: 10.2210/pdb2o26/pdb
• Related: 2O27
• Descriptor: Kit ligand, Mast/stem cell growth factor receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: stem cell factor, receptor tyrosine kinase, class iii, receptor-ligand complex, growth factor, cytokine, 4-helix bundle, cytokine-signaling protein complex, cytokine/signaling protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 199505.66

Authors

Liu, H.,Chen, X.,Focia, P.J.,He, X. (deposition date: 2006-11-29, release date: 2007-03-13, Last modification date: 2023-12-27)

• Primary citation: Liu, H.,Chen, X.,Focia, P.J.,He, X.; Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.; Embo J., 26:891-901, 2007; PubMed: 17255936; DOI: 10.1038/sj.emboj.7601545

Experimental method

X-RAY DIFFRACTION (2.5 Å)