2NPH

Crystal structure of HIV1 protease in situ product complex

Summary for 2NPH

Entry DOI	10.2210/pdb2nph/pdb
Related	1G6L 1LV1
Descriptor	PROTEASE RETROPEPSIN, tetrapeptide fragment, pentapeptide fragment, ... (4 entities in total)
Functional Keywords	anti-parallel beta sheet, hydrolase
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	4
Total formula weight	22625.58
Authors	Hosur, M.V.,Das, A.,Prashar, V. (deposition date: 2006-10-27, release date: 2006-12-19, Last modification date: 2023-12-27)
Primary citation	Das, A.,Prashar, V.,Mahale, S.,Serre, L.,Ferrer, J.-L.,Hosur, M.V. Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates Proc.Natl.Acad.Sci.Usa, 103:18464-18469, 2006 Cited by PubMed: 17116869 DOI: 10.1073/pnas.0605809103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation