2NNY

Crystal structure of the Ets1 dimer DNA complex.

Summary for 2NNY

• Entry DOI: 10.2210/pdb2nny/pdb
• Related: 1GVJ 1K78
• Descriptor: 5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3', 5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3', C-ets-1 protein, ... (4 entities in total)
• Functional Keywords: ets-1, protein-dna complex, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P14921
• Total number of polymer chains: 4
• Total formula weight: 53879.06

Authors

Lamber, E.P.,Kachalova, G.S.,Wilmanns, M. (deposition date: 2006-10-24, release date: 2008-03-04, Last modification date: 2023-08-30)

• Primary citation: Lamber, E.P.,Vanhille, L.,Textor, L.C.,Kachalova, G.S.,Sieweke, M.H.,Wilmanns, M.; Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.; Embo J., 27:2006-2017, 2008; PubMed: 18566588; DOI: 10.1038/emboj.2008.117

Experimental method

X-RAY DIFFRACTION (2.58 Å)