2NNR

Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi

Summary for 2NNR

• Entry DOI: 10.2210/pdb2nnr/pdb
• Related: 2FO8 2H7W
• Descriptor: Chagasin, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: chagasin, deformed jelly roll, predominately beta structure, hydrolase inhibitor
• Biological source: Trypanosoma cruzi
• Cellular location: Flagellar pocket : Q966X9
• Total number of polymer chains: 2
• Total formula weight: 24885.13

Authors

Redzynia, I.,Bujacz, G.,Ljunggren, A.,Jaskolski, M.,Abrahamson, M. (deposition date: 2006-10-24, release date: 2007-07-24, Last modification date: 2023-12-27)

• Primary citation: Ljunggren, A.,Redzynia, I.,Alvarez-Fernandez, M.,Abrahamson, M.,Mort, J.S.,Krupa, J.C.,Jaskolski, M.,Bujacz, G.; Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease; J.Mol.Biol., 371:137-153, 2007; PubMed: 17561110; DOI: 10.1016/j.jmb.2007.05.005

Experimental method

X-RAY DIFFRACTION (1.7 Å)