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2NDH

NMR solution structure of MAL/TIRAP TIR domain (C116A)

Summary for 2NDH
Entry DOI10.2210/pdb2ndh/pdb
Related2YP2 3UB2 4FZ5 4LQD
NMR InformationBMRB: 26061
DescriptorToll/interleukin-1 receptor domain-containing adapter protein (1 entity in total)
Functional Keywordsimmune system
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P58753
Total number of polymer chains1
Total formula weight15726.88
Authors
Lavrencic, P.,Mobli, M. (deposition date: 2016-05-27, release date: 2017-05-31, Last modification date: 2023-06-14)
Primary citationHughes, M.M.,Lavrencic, P.,Coll, R.C.,Ve, T.,Ryan, D.G.,Williams, N.C.,Menon, D.,Mansell, A.,Board, P.G.,Mobli, M.,Kobe, B.,O'Neill, L.A.J.
Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.
Proc. Natl. Acad. Sci. U.S.A., 114:E6480-E6489, 2017
Cited by
PubMed: 28739909
DOI: 10.1073/pnas.1701868114
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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