2NDH
NMR solution structure of MAL/TIRAP TIR domain (C116A)
Summary for 2NDH
Entry DOI | 10.2210/pdb2ndh/pdb |
Related | 2YP2 3UB2 4FZ5 4LQD |
NMR Information | BMRB: 26061 |
Descriptor | Toll/interleukin-1 receptor domain-containing adapter protein (1 entity in total) |
Functional Keywords | immune system |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P58753 |
Total number of polymer chains | 1 |
Total formula weight | 15726.88 |
Authors | Lavrencic, P.,Mobli, M. (deposition date: 2016-05-27, release date: 2017-05-31, Last modification date: 2023-06-14) |
Primary citation | Hughes, M.M.,Lavrencic, P.,Coll, R.C.,Ve, T.,Ryan, D.G.,Williams, N.C.,Menon, D.,Mansell, A.,Board, P.G.,Mobli, M.,Kobe, B.,O'Neill, L.A.J. Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. Proc. Natl. Acad. Sci. U.S.A., 114:E6480-E6489, 2017 Cited by PubMed: 28739909DOI: 10.1073/pnas.1701868114 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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