2NCZ

Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide

Summary for 2NCZ

• Entry DOI: 10.2210/pdb2ncz/pdb
• Related: 2ND0 2ND1
• NMR Information: BMRB: 26041
• Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3 (2 entities in total)
• Functional Keywords: transcription, transferase, transcription-transferase complex, transcription/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: O60885 Q9BZ95
• Total number of polymer chains: 2
• Total formula weight: 11176.88

Authors

Zeng, L.,Zhou, M. (deposition date: 2016-04-18, release date: 2016-06-29, Last modification date: 2016-07-20)

• Primary citation: Zhang, Q.,Zeng, L.,Shen, C.,Ju, Y.,Konuma, T.,Zhao, C.,Vakoc, C.R.,Zhou, M.M.; Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.; Structure, 24:1201-1208, 2016; PubMed: 27291650; DOI: 10.1016/j.str.2016.04.019

Experimental method

SOLUTION NMR