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2NA7

Transmembrane domain of human Fas/CD95 death receptor

Summary for 2NA7
Entry DOI10.2210/pdb2na7/pdb
Related2NA6
NMR InformationBMRB: 25930
DescriptorTumor necrosis factor receptor superfamily member 6 (1 entity in total)
Functional Keywordstransmembrane helix trimer, transmembrane domain, proline-containing motif, apoptosis, structural genomics, psi-biology, membrane protein structures by solution nmr, mpsbynmr
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted. Isoform 6: Secreted: P25445
Total number of polymer chains3
Total formula weight9918.18
Authors
Fu, Q.,Chou, J.J.,Membrane Protein Structures by Solution NMR (MPSbyNMR) (deposition date: 2015-12-21, release date: 2016-01-27, Last modification date: 2023-06-14)
Primary citationFu, Q.,Fu, T.M.,Cruz, A.C.,Sengupta, P.,Thomas, S.K.,Wang, S.,Siegel, R.M.,Wu, H.,Chou, J.J.
Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.
Mol.Cell, 61:602-613, 2016
Cited by
PubMed: 26853147
DOI: 10.1016/j.molcel.2016.01.009
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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