2N8F
Chemical shift assignments and structure calculation of spider toxin pi-hexatoxin-Hi1a
Summary for 2N8F
| Entry DOI | 10.2210/pdb2n8f/pdb |
| NMR Information | BMRB: 25848 |
| Descriptor | spider toxin pi-hexatoxin-Hi1a (1 entity in total) |
| Functional Keywords | spider toxin, inhibitor cystine knot, double knot toxin, asic1a antagonist, ion channel modulator, toxin |
| Biological source | Hadronyche infensa |
| Total number of polymer chains | 1 |
| Total formula weight | 8750.20 |
| Authors | Chin, Y.K.-Y.,Pineda, S.S.,Mobli, M.,King, G.F. (deposition date: 2015-10-13, release date: 2016-10-19, Last modification date: 2023-06-14) |
| Primary citation | Chassagnon, I.R.,McCarthy, C.A.,Chin, Y.K.,Pineda, S.S.,Keramidas, A.,Mobli, M.,Pham, V.,De Silva, T.M.,Lynch, J.W.,Widdop, R.E.,Rash, L.D.,King, G.F. Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a. Proc. Natl. Acad. Sci. U.S.A., 114:3750-3755, 2017 Cited by PubMed: 28320941DOI: 10.1073/pnas.1614728114 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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