2N8A
1H, 13C and 15N chemical shift assignments and solution structure for PARP-1 F1F2 domains in complex with a DNA single-strand break
Summary for 2N8A
Entry DOI | 10.2210/pdb2n8a/pdb |
NMR Information | BMRB: 25888 |
Descriptor | Poly [ADP-ribose] polymerase 1, DNA (45-MER), ZINC ION (3 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P09874 |
Total number of polymer chains | 2 |
Total formula weight | 38109.25 |
Authors | Neuhaus, D.,Eustermann, S.,Yang, J.,Wu, W. (deposition date: 2015-10-08, release date: 2015-12-02, Last modification date: 2016-10-19) |
Primary citation | Eustermann, S.,Wu, W.F.,Langelier, M.F.,Yang, J.C.,Easton, L.E.,Riccio, A.A.,Pascal, J.M.,Neuhaus, D. Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1. Mol.Cell, 60:742-754, 2015 Cited by PubMed: 26626479DOI: 10.1016/j.molcel.2015.10.032 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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