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2N8A

1H, 13C and 15N chemical shift assignments and solution structure for PARP-1 F1F2 domains in complex with a DNA single-strand break

Summary for 2N8A
Entry DOI10.2210/pdb2n8a/pdb
NMR InformationBMRB: 25888
DescriptorPoly [ADP-ribose] polymerase 1, DNA (45-MER), ZINC ION (3 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P09874
Total number of polymer chains2
Total formula weight38109.25
Authors
Neuhaus, D.,Eustermann, S.,Yang, J.,Wu, W. (deposition date: 2015-10-08, release date: 2015-12-02, Last modification date: 2016-10-19)
Primary citationEustermann, S.,Wu, W.F.,Langelier, M.F.,Yang, J.C.,Easton, L.E.,Riccio, A.A.,Pascal, J.M.,Neuhaus, D.
Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.
Mol.Cell, 60:742-754, 2015
Cited by
PubMed: 26626479
DOI: 10.1016/j.molcel.2015.10.032
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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