2N5S
Spatial structure of EGFR transmembrane and juxtamembrane domains in DPC micelles
Summary for 2N5S
| Entry DOI | 10.2210/pdb2n5s/pdb |
| NMR Information | BMRB: 25729 |
| Descriptor | Epidermal growth factor receptor (1 entity in total) |
| Functional Keywords | transmembrane, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533 |
| Total number of polymer chains | 1 |
| Total formula weight | 5979.34 |
| Authors | Mineev, K.,Bocharov, E.,Bocharova, O.,Arseniev, A. (deposition date: 2015-07-27, release date: 2015-10-14, Last modification date: 2023-06-14) |
| Primary citation | Mineev, K.S.,Panova, S.V.,Bocharova, O.V.,Bocharov, E.V.,Arseniev, A.S. The Membrane Mimetic Affects the Spatial Structure and Mobility of EGFR Transmembrane and Juxtamembrane Domains. Biochemistry, 54:6295-6298, 2015 Cited by PubMed: 26440883DOI: 10.1021/acs.biochem.5b00851 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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