2N3W

Solution structure of the Rpn1 T1 site with K48-linked diubiquitin in the contracted binding mode

Summary for 2N3W

• Entry DOI: 10.2210/pdb2n3w/pdb
• Related: 2N3T 2N3U 2N3V
• Descriptor: 26S proteasome regulatory subunit RPN1, Ubiquitin-60S ribosomal protein L40 (2 entities in total)
• Functional Keywords: protein binding
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm : P62987
• Total number of polymer chains: 3
• Total formula weight: 30790.25

Authors

Chen, X.,Walters, K.J. (deposition date: 2015-06-10, release date: 2016-02-24, Last modification date: 2023-06-14)

• Primary citation: Shi, Y.,Chen, X.,Elsasser, S.,Stocks, B.B.,Tian, G.,Lee, B.H.,Shi, Y.,Zhang, N.,de Poot, S.A.,Tuebing, F.,Sun, S.,Vannoy, J.,Tarasov, S.G.,Engen, J.R.,Finley, D.,Walters, K.J.; Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.; Science, 351:-, 2016; PubMed: 26912900; DOI: 10.1126/science.aad9421

Experimental method

SOLUTION NMR