2N1F
Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy
Summary for 2N1F
Entry DOI | 10.2210/pdb2n1f/pdb |
EMDB information | 2971 |
NMR Information | BMRB: 26550 |
Descriptor | Apoptosis-associated speck-like protein (1 entity in total) |
Functional Keywords | mouse asc filament, asc apoptosis-associated speck like protein containing a card, pyrin domain, inflammasomes, death domain, apoptosis |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 15 |
Total formula weight | 151780.26 |
Authors | Sborgi, L.,Ravotti, F.,Dandey, V.,Dick, M.,Mazur, A.,Reckel, S.,Chami, M.,Scherer, S.,Bockmann, A.,Egelman, E.,Stahlberg, H.,Broz, P.,Meier, B.,Hiller, S. (deposition date: 2015-04-01, release date: 2015-10-14, Last modification date: 2023-06-14) |
Primary citation | Sborgi, L.,Ravotti, F.,Dandey, V.P.,Dick, M.S.,Mazur, A.,Reckel, S.,Chami, M.,Scherer, S.,Huber, M.,Bockmann, A.,Egelman, E.H.,Stahlberg, H.,Broz, P.,Meier, B.H.,Hiller, S. Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 112:13237-13242, 2015 Cited by PubMed: 26464513DOI: 10.1073/pnas.1507579112 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) SOLID-STATE NMR (4 Å) |
Structure validation
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