2MZI

NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Anionic Membrane

Summary for 2MZI

• Entry DOI: 10.2210/pdb2mzi/pdb
• Related: 2mze 2mzh
• NMR Information: BMRB: 25489
• Descriptor: Matrilysin, CALCIUM ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: zymogen, hydrolase, membrane-bound form, metalloenzyme, anionic
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix : P09237
• Total number of polymer chains: 1
• Total formula weight: 116470.29

Authors

Prior, S.H.,Van Doren, S.R. (deposition date: 2015-02-12, release date: 2016-09-28, Last modification date: 2023-06-14)

• Primary citation: Prior, S.H.,Fulcher, Y.G.,Koppisetti, R.K.,Jurkevich, A.,Van Doren, S.R.; Charge-Triggered Membrane Insertion of Matrix Metalloproteinase-7, Supporter of Innate Immunity and Tumors.; Structure, 23:2099-2110, 2015; PubMed: 26439767; DOI: 10.1016/j.str.2015.08.013

Experimental method

SOLUTION NMR