2MAS
PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR
Summary for 2MAS
| Entry DOI | 10.2210/pdb2mas/pdb |
| Descriptor | INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE, CALCIUM ION, 2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL, ... (4 entities in total) |
| Functional Keywords | purine nucleoside hydrolase, inosine, uridine, iu-nh, hydrolase, purine nucleosidase |
| Biological source | Crithidia fasciculata |
| Total number of polymer chains | 4 |
| Total formula weight | 137883.26 |
| Authors | Degano, M.,Schramm, V.L.,Sacchettini, J.C. (deposition date: 1996-10-17, release date: 1997-08-12, Last modification date: 2023-08-09) |
| Primary citation | Degano, M.,Almo, S.C.,Sacchettini, J.C.,Schramm, V.L. Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor. Biochemistry, 37:6277-6285, 1998 Cited by PubMed: 9572842DOI: 10.1021/bi973012e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report
