2LYA

Structure of HIV-1 myr(-) matrix protein in complex with 1,2-dioctanoyl-sn-phosphatidylcholine

Summary for 2LYA

• Entry DOI: 10.2210/pdb2lya/pdb
• Related: 2LYB
• NMR Information: BMRB: 18715
• Descriptor: Matrix protein p17, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (2 entities in total)
• Functional Keywords: gag, matrix, plasma membrane, lipid, viral protein
• Biological source: Human immunodeficiency virus type 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• Total number of polymer chains: 1
• Total formula weight: 16074.12

Authors

Vlach, J.,Saad, J. (deposition date: 2012-09-14, release date: 2013-02-13, Last modification date: 2013-04-03)

• Primary citation: Vlach, J.,Saad, J.S.; Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.; Proc.Natl.Acad.Sci.USA, 110:3525-3530, 2013; PubMed: 23401539; DOI: 10.1073/pnas.1216655110

Experimental method

SOLUTION NMR