2LY0
Solution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332
Summary for 2LY0
| Entry DOI | 10.2210/pdb2ly0/pdb |
| NMR Information | BMRB: 18706 |
| Descriptor | Membrane ion channel M2, (3S,5S,7S)-N-{[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methyl}tricyclo[3.3.1.1~3,7~]decan-1-aminium (2 entities in total) |
| Functional Keywords | influenza a virus, m2 channel, s31n inhibitor, viral protein |
| Biological source | Influenza A virus |
| Total number of polymer chains | 4 |
| Total formula weight | 14303.92 |
| Authors | Wu, Y.,Wang, J.,DeGrado, W. (deposition date: 2012-09-10, release date: 2013-01-09, Last modification date: 2023-06-14) |
| Primary citation | Wang, J.,Wu, Y.,Ma, C.,Fiorin, G.,Wang, J.,Pinto, L.H.,Lamb, R.A.,Klein, M.L.,Degrado, W.F. Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus. Proc.Natl.Acad.Sci.USA, 110:1315-1320, 2013 Cited by PubMed: 23302696DOI: 10.1073/pnas.1216526110 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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