2LVM

Solution structure of human 53BP1 tandem Tudor domains in complex with a histone H4K20me2 peptide

Summary for 2LVM

• Entry DOI: 10.2210/pdb2lvm/pdb
• NMR Information: BMRB: 18579
• Descriptor: Tumor suppressor p53-binding protein 1, Histone H4 (2 entities in total)
• Functional Keywords: dimethylation, cell cycle
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q12888 P62805
• Total number of polymer chains: 2
• Total formula weight: 15668.82

Authors

Cui, G.,Botuyan, M.,Mer, G. (deposition date: 2012-07-07, release date: 2012-12-12, Last modification date: 2013-04-03)

• Primary citation: Tang, J.,Cho, N.W.,Cui, G.,Manion, E.M.,Shanbhag, N.M.,Botuyan, M.V.,Mer, G.,Greenberg, R.A.; Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.; Nat.Struct.Mol.Biol., 20:317-325, 2013; PubMed: 23377543; DOI: 10.1038/nsmb.2499

Experimental method

SOLUTION NMR