2LTZ

Smurf2 WW3 domain in complex with a Smad7 derived peptide

Summary for 2LTZ

• Entry DOI: 10.2210/pdb2ltz/pdb
• Related: 2LTV 2LTW 2LTX 2LTY
• NMR Information: BMRB: 18502
• Descriptor: E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide (2 entities in total)
• Functional Keywords: ww, smurf2, smad7, protein binding-peptide complex, protein binding/peptide
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9HAU4 O15105
• Total number of polymer chains: 2
• Total formula weight: 5983.55

Authors

Macias, M.J.,Aragon, E.,Goerner, N.,Xi, Q.,Lopes, T.,Gao, S.,Massague, J. (deposition date: 2012-06-04, release date: 2012-11-21)

• Primary citation: Aragon, E.,Goerner, N.,Xi, Q.,Gomes, T.,Gao, S.,Massague, J.,Macias, M.J.; Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.; Structure, 20:1726-1736, 2012; PubMed: 22921829; DOI: 10.1016/j.str.2012.07.014

Experimental method

SOLUTION NMR