2LTY
NEDD4L WW2 domain in complex with a Smad7 derived peptide
Summary for 2LTY
| Entry DOI | 10.2210/pdb2lty/pdb |
| Related | 2LTV 2LTW 2LTX 2LTZ |
| NMR Information | BMRB: 18501 |
| Descriptor | E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide (2 entities in total) |
| Functional Keywords | ww, nedd4l, smad7, protein binding-peptide complex, protein binding/peptide |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm: Q96PU5 Nucleus: O15105 |
| Total number of polymer chains | 2 |
| Total formula weight | 5745.32 |
| Authors | Macias, M.J.,Aragon, E.,Goerner, N.,Xi, Q.,Lopes, T.,Gao, S.,Massague, J. (deposition date: 2012-06-04, release date: 2012-11-21) |
| Primary citation | Aragon, E.,Goerner, N.,Xi, Q.,Gomes, T.,Gao, S.,Massague, J.,Macias, M.J. Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20:1726-1736, 2012 Cited by PubMed: 22921829DOI: 10.1016/j.str.2012.07.014 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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