2LEH

Solution structure of the core SMN-Gemin2 complex

Summary for 2LEH

Entry DOI	10.2210/pdb2leh/pdb
NMR Information	BMRB: 17711
Descriptor	Survival of motor neuron protein-interacting protein 1, Survival motor neuron protein (2 entities in total)
Functional Keywords	spinal muscular atrophy, snrnp assembly, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Nucleus, gem: O14893 Cytoplasm: Q16637
Total number of polymer chains	2
Total formula weight	24472.51
Authors	Sarachan, K.L.,Valentine, K.,Gupta, K.,Moorman, V.,Gledhill, J.,Bernens, M.,Tommos, C.,Wand, A.J.,Van Duyne, G. (deposition date: 2011-06-15, release date: 2012-06-27, Last modification date: 2021-08-18)
Primary citation	Sarachan, K.L.,Valentine, K.G.,Gupta, K.,Moorman, V.R.,Gledhill Jr, J.M.,Bernens, M.,Tommos, C.,Wand, A.J.,Van Duyne, G.D. Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445:361-370, 2012 Cited by PubMed: 22607171 DOI: 10.1042/BJ20120241 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation