2LDR
Solution structure of Helix-RING domain of Cbl-b in the Tyr363 phosphorylated form
Summary for 2LDR
| Entry DOI | 10.2210/pdb2ldr/pdb |
| NMR Information | BMRB: 17680 |
| Descriptor | E3 ubiquitin-protein ligase CBL-B, ZINC ION (2 entities in total) |
| Functional Keywords | e3 ligase, ubiquitin, ring domain, ligase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q13191 |
| Total number of polymer chains | 1 |
| Total formula weight | 9395.29 |
| Authors | Kumeta, H.,Kobashigawa, Y.,Inagaki, F. (deposition date: 2011-06-01, release date: 2011-12-14, Last modification date: 2023-06-14) |
| Primary citation | Kobashigawa, Y.,Tomitaka, A.,Kumeta, H.,Noda, N.N.,Yamaguchi, M.,Inagaki, F. Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108:20579-20584, 2011 Cited by PubMed: 22158902DOI: 10.1073/pnas.1110712108 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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