2L84

Solution NMR structures of CBP bromodomain with small molecule j28

Summary for 2L84

Entry DOI	10.2210/pdb2l84/pdb
NMR Information	BMRB: 17392
Descriptor	CREB-binding protein, 5-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid (2 entities in total)
Functional Keywords	p53, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q92793
Total number of polymer chains	1
Total formula weight	14753.93
Authors	Borah, J.C.,Mujtaba, S.,Karakikes, I.,Zeng, L.,Muller, M.,Patel, J.,Moshkina, N.,Morohashi, K.,Zhang, W.,Gerona-Navarro, G.,Hajjar, R.J.,Zhou, M. (deposition date: 2011-01-03, release date: 2011-01-19, Last modification date: 2011-07-13)
Primary citation	Borah, J.C.,Mujtaba, S.,Karakikes, I.,Zeng, L.,Muller, M.,Patel, J.,Moshkina, N.,Morohashi, K.,Zhang, W.,Gerona-Navarro, G.,Hajjar, R.J.,Zhou, M.M. A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes. Chem.Biol., 18:531-541, 2011 Cited by PubMed: 21513889 DOI: 10.1016/j.chembiol.2010.12.021 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation