2L5J
structure of the spliceosomal phosphopeptide P140 (phosphorylated form)
Summary for 2L5J
| Entry DOI | 10.2210/pdb2l5j/pdb |
| Related | 2L5I |
| Descriptor | U1 small nuclear ribonucleoprotein 70 kDa (1 entity in total) |
| Functional Keywords | phosphorylation, hsc70, lupus, splicing |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: P08621 |
| Total number of polymer chains | 1 |
| Total formula weight | 2644.99 |
| Authors | Quinternet, M.,Page, N.,Schall, N.,Strub, J.,Chaloin, O.,Decossas, M.,Cung, M.,van Dorsselaer, A.,Briand, J.,Muller, S. (deposition date: 2010-11-02, release date: 2010-12-01, Last modification date: 2011-07-13) |
| Primary citation | Page, N.,Schall, N.,Strub, J.M.,Quinternet, M.,Chaloin, O.,Decossas, M.,Cung, M.T.,Van Dorsselaer, A.,Briand, J.P.,Muller, S. The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells. Plos One, 4:e5273-e5273, 2009 Cited by PubMed: 19390596DOI: 10.1371/journal.pone.0005273 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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