2L4L

Structural insights into the cTAR DNA recognition by the HIV-1 Nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC

Summary for 2L4L

• Entry DOI: 10.2210/pdb2l4l/pdb
• Descriptor: HIV-1 nucleocapsid protein NCp7, 5'-D(*CP*TP*GP*G)-3', ZINC ION (3 entities in total)
• Functional Keywords: nc(11-55):mini-ctar, viral protein-dna complex, viral protein/dna
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 6489.65

Authors

Bazzi, A.,Zargarian, L.,Chaminade, F.,Boudier, C.,De Rocquigny, H.,Rene, B.,Mely, Y.,Fosse, P.,Mauffret, O. (deposition date: 2010-10-08, release date: 2010-12-08, Last modification date: 2011-08-17)

• Primary citation: Bazzi, A.,Zargarian, L.,Chaminade, F.,Boudier, C.,De Rocquigny, H.,Rene, B.,Mely, Y.,Fosse, P.,Mauffret, O.; Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC.; Nucleic Acids Res., 39:3903-3916, 2011; PubMed: 21227929; DOI: 10.1093/nar/gkq1290

Experimental method

SOLUTION NMR