2KWN

Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing acetylation at Lysine 16

Summary for 2KWN

• Entry DOI: 10.2210/pdb2kwn/pdb
• Related: 2kwj 2kwk 2kwo
• NMR Information: BMRB: 16861
• Descriptor: Histone peptide, Zinc finger protein DPF3, ZINC ION (3 entities in total)
• Functional Keywords: acetyl-lysine, transcription regulation, nucleus, metal binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus (Probable): Q92784
• Total number of polymer chains: 2
• Total formula weight: 14689.15

Authors

Zeng, L.,Zhang, Q.,Li, S.,Plotnikov, A.N.,Walsh, M.J.,Zhou, M. (deposition date: 2010-04-13, release date: 2010-07-14, Last modification date: 2023-11-15)

• Primary citation: Zeng, L.,Zhang, Q.,Li, S.,Plotnikov, A.N.,Walsh, M.J.,Zhou, M.M.; Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.; Nature, 466:258-262, 2010; PubMed: 20613843; DOI: 10.1038/nature09139

Experimental method

SOLUTION NMR