2KWF

The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1

Summary for 2KWF

• Entry DOI: 10.2210/pdb2kwf/pdb
• NMR Information: BMRB: 16851
• Descriptor: CREB-binding protein, Transcription factor 4 (2 entities in total)
• Functional Keywords: transcription, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q92793; Nucleus (Probable): P15884
• Total number of polymer chains: 2
• Total formula weight: 12375.04

Authors

Denis, C.M.,Chitayat, S.,Plevin, M.J.,Liu, S.,Spencer, H.L.,Ikura, M.,LeBrun, D.P.,Smith, S.P. (deposition date: 2010-04-08, release date: 2011-07-20)

• Primary citation: Denis, C.M.,Chitayat, S.,Plevin, M.J.,Liu, S.,Spencer, H.L.,Ikura, M.,LeBrun, D.P.,Smith, S.P.; The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1; To be Published,

Experimental method

SOLUTION NMR