2KQ6
The structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity
Summary for 2KQ6
| Entry DOI | 10.2210/pdb2kq6/pdb |
| NMR Information | BMRB: 16590 |
| Descriptor | Polycystin-2 (1 entity in total) |
| Functional Keywords | protein x, calcium, coiled coil, disease mutation, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, polymorphism, transmembrane, transport, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 9009.58 |
| Authors | Petri, E.T.,Celic, A.,Kennedy, S.D.,Ehrlich, B.E.,Boggon, T.J.,Hodsdon, M.E. (deposition date: 2009-10-28, release date: 2010-05-12, Last modification date: 2023-06-14) |
| Primary citation | Petri, E.T.,Celic, A.,Kennedy, S.D.,Ehrlich, B.E.,Boggon, T.J.,Hodsdon, M.E. Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity. Proc.Natl.Acad.Sci.USA, 107:9176-9181, 2010 Cited by PubMed: 20439752DOI: 10.1073/pnas.0912295107 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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