2KBI
Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5
Summary for 2KBI
| Entry DOI | 10.2210/pdb2kbi/pdb |
| NMR Information | BMRB: 16045 |
| Descriptor | Sodium channel protein type 5 subunit alpha (1 entity in total) |
| Functional Keywords | protein, ef-hand, sodium channel, brugada syndrome, cardiomyopathy, disease mutation, glycoprotein, ion transport, ionic channel, long qt syndrome, membrane, phosphoprotein, polymorphism, sodium, sodium transport, transmembrane, transport, ubl conjugation, voltage-gated channel, metal binding protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Multi-pass membrane protein: Q14524 |
| Total number of polymer chains | 1 |
| Total formula weight | 10994.21 |
| Authors | Chagot, B.,Potet, F.,Balser, J.R.,Chazin, W.J. (deposition date: 2008-11-28, release date: 2008-12-23, Last modification date: 2022-03-16) |
| Primary citation | Chagot, B.,Potet, F.,Balser, J.R.,Chazin, W.J. Solution NMR Structure of the C-terminal EF-hand Domain of Human Cardiac Sodium Channel NaV1.5. J.Biol.Chem., 284:6436-6445, 2009 Cited by PubMed: 19074138DOI: 10.1074/jbc.M807747200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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