2KA6

NMR structure of the CBP-TAZ2/STAT1-TAD complex

2KA6 の概要

• エントリーDOI: 10.2210/pdb2ka6/pdb
• 関連するPDBエントリー: 2KA4
• NMR情報: BMRB: 16015
• 分子名称: CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION (3 entities in total)
• 機能のキーワード: cbp/p300, taz2, stat1, transactivation domain, bromodomain, activator, alternative splicing, antiviral defense, cytoplasm, disease mutation, dna-binding, host-virus interaction, nucleus, phosphoprotein, polymorphism, sh2 domain, transcription, transcription regulation, transcription regulator, acetylation, chromosomal rearrangement, metal-binding, methylation, transferase, ubl conjugation, zinc, zinc-finger
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15765.38

構造登録者

Wojciak, J.M.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E. (登録日: 2008-10-30, 公開日: 2009-04-07, 最終更新日: 2021-10-20)

• 主引用文献: Wojciak, J.M.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E.; Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.; Embo J., 28:948-958, 2009; PubMed: 19214187; DOI: 10.1038/emboj.2009.30

実験手法

SOLUTION NMR