2JUM

ThrA3-DKP-insulin

Summary for 2JUM

• Entry DOI: 10.2210/pdb2jum/pdb
• Related: 2JUU 2JUV
• NMR Information: BMRB: 15450
• Descriptor: Insulin A chain, Insulin B chain (2 entities in total)
• Functional Keywords: insulin, thra3, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, pharmaceutical, secreted
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 5796.56

Authors

Huang, K.,Chan, S.,Hua, Q.,Chu, Y.,Wang, R.,Klaproth, B.,Jia, W.,Whittaker, J.,De Meyts, P.,Nakagawa, S.H.,Steiner, D.F.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2007-08-31, release date: 2007-10-16, Last modification date: 2021-10-20)

• Primary citation: Huang, K.,Chan, S.J.,Hua, Q.X.,Chu, Y.C.,Wang, R.Y.,Klaproth, B.,Jia, W.,Whittaker, J.,De Meyts, P.,Nakagawa, S.H.,Steiner, D.F.,Katsoyannis, P.G.,Weiss, M.A.; The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.; J.Biol.Chem., 282:35337-35349, 2007; PubMed: 17884811; DOI: 10.1074/jbc.M705996200

Experimental method

SOLUTION NMR