2JTT

Solution structure of calcium loaded S100A6 bound to C-terminal Siah-1 interacting protein

Summary for 2JTT

• Entry DOI: 10.2210/pdb2jtt/pdb
• Related: 1JWD
• NMR Information: BMRB: 15418
• Descriptor: Protein S100-A6, Calcyclin-binding protein (2 entities in total)
• Functional Keywords: s100a6, siah-1 interacting protein, ubiquitination, e3 ligase complex, beta-catenin, calcium, cell cycle, mitogen, cytoplasm, nucleus, phosphorylation, ubl conjugation pathway, calcium binding protein-antitumor protein complex, calcium binding protein/antitumor protein
• Biological source: Oryctolagus cuniculus (rabbit); More
• Cellular location: Nucleus envelope (By similarity): P30801; Nucleus: Q9CXW3
• Total number of polymer chains: 4
• Total formula weight: 28228.31

Authors

Lee, Y.,Chazin, W.J. (deposition date: 2007-08-06, release date: 2008-08-19, Last modification date: 2022-03-16)

• Primary citation: Lee, Y.T.,Dimitrova, Y.N.,Schneider, G.,Ridenour, W.B.,Bhattacharya, S.,Soss, S.E.,Caprioli, R.M.,Filipek, A.,Chazin, W.J.; Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition.; Biochemistry, 47:10921-10932, 2008; PubMed: 18803400; DOI: 10.1021/bi801233z

Experimental method

SOLUTION NMR