2JRI

Solution structure of the Josephin domain of Ataxin-3 in complex with ubiquitin molecule.

Summary for 2JRI

• Entry DOI: 10.2210/pdb2jri/pdb
• Related: 1YZB
• Descriptor: Ataxin-3, UBC protein (2 entities in total)
• Functional Keywords: di-ubiquitin, lys48-linked, josephin domain of ataxin-3, spinocerebellar ataxia type 3 protein, alternative splicing, hydrolase, neurodegeneration, nucleus, phosphorylation, polymorphism, transcription, transcription regulation, triplet repeat expansion, hydrolase-signaling protein complex, hydrolase/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus matrix: P54252
• Total number of polymer chains: 3
• Total formula weight: 38207.43

Authors

Nicastro, G.,Masino, L.,Esposito, V.,Menon, R.,Pastore, A. (deposition date: 2007-06-27, release date: 2008-07-01, Last modification date: 2022-03-09)

• Primary citation: Nicastro, G.,Menon, R.,Masino, L.,Pastore, A.; Understanding the plasticity of the ubiquitin-protein recognition code: the josephin domain of ataxin-3 is a diubiquitin binding motif; To be Published,

Experimental method

SOLUTION NMR