2JG8

Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine

Summary for 2JG8

• Entry DOI: 10.2210/pdb2jg8/pdb
• Related: 1PK6 2JG9
• Descriptor: Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... (7 entities in total)
• Functional Keywords: polymorphism, glycoprotein, phagocytosis, disease mutation, complement pathway, immune system, cell surface molecule, pyrrolidone carboxylic acid, hydroxylation, innate immunity, immune response, collagen, tolerance, apopotosis, complement
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 90374.15

Authors

Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P. (deposition date: 2007-02-09, release date: 2008-02-19, Last modification date: 2023-12-13)

• Primary citation: Paidassi, H.,Tacnet-Delorme, P.,Garlatti, V.,Darnault, C.,Ghebrehiwet, B.,Gaboriaud, C.,Arlaud, G.J.,Frachet, P.; C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition.; J.Immunol., 180:2329-2338, 2008; PubMed: 18250442; DOI: 10.4049/jimmunol.180.4.2329

Experimental method

X-RAY DIFFRACTION (2.05 Å)