2JFD
Structure of the MAT domain of human FAS
Summary for 2JFD
| Entry DOI | 10.2210/pdb2jfd/pdb |
| Related | 1XKT 2CG5 |
| Descriptor | FATTY ACID SYNTHASE (2 entities in total) |
| Functional Keywords | transferase, oxidoreductase, lipid synthesis, fatty acid biosynthesis |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cytoplasm : P49327 |
| Total number of polymer chains | 4 |
| Total formula weight | 186946.84 |
| Authors | Bunkoczi, G.,Kavanagh, K.,Hozjan, V.,Rojkova, A.,Wu, X.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Smith, S.,Oppermann, U. (deposition date: 2007-01-31, release date: 2007-02-13, Last modification date: 2018-02-28) |
| Primary citation | Bunkoczi, G.,Misquitta, S.,Wu, X.,Lee, W.H.,Rojkova, A.,Kochan, G.,Kavanagh, K.L.,Oppermann, U.,Smith, S. Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases. Chem. Biol., 16:667-675, 2009 Cited by PubMed: 19549604DOI: 10.1016/j.chembiol.2009.04.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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