2JF4

Family 37 trehalase from Escherichia coli in complex with validoxylamine

Summary for 2JF4

Entry DOI	10.2210/pdb2jf4/pdb
Descriptor	PERIPLASMIC TREHALASE, (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL (3 entities in total)
Functional Keywords	family 37, hydrolase, inhibitor, trehalase, glycoside hydrolase, periplasmic, glycosidase, validoxylamine
Biological source	ESCHERICHIA COLI
Cellular location	Periplasm: P13482
Total number of polymer chains	1
Total formula weight	61518.40
Authors	Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J. (deposition date: 2007-01-25, release date: 2007-02-13, Last modification date: 2011-07-13)
Primary citation	Gibson, R.P.,Gloster, T.M.,Roberts, S.,Warren, R.A.J.,Storch De Gracia, I.,Garcia, A.,Chiara, J.L.,Davies, G.J. Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors. Angew.Chem.Int.Ed.Engl., 46:4115-, 2007 Cited by PubMed: 17455176 DOI: 10.1002/ANIE.200604825 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation